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General, Organic, and Biological Chemistry: An Integrated Approach

By Laura D. Frost, S. Todd Deal, Karen C. Timberlake

Published by Pearson

Published Date: Jan 5, 2010


Drawing on 20 years of teaching allied health and pre-professional students, authors Laura Frost and Todd Deal have created this innovative new text for your GOB chemistry course.  General, organic, and biological chemistry topics are integrated throughout each chapter in a manner that immediately relates chemistry to your future allied health career and everyday life. General, Organic, and Biological Chemistry: An Integrated Approach introduces the problem-solving skills you will need to assess situations critically on the job. Unique guided-inquiry activities are incorporated after each chapter, guiding you through an exploration of the information to develop chemical concepts, and then apply the developed concept to further examples.

Table of Contents

NOTE: Each chapter concludes with Summary, Key Terms, Important Equations, Additional Problems, Challenge Problems, Answers to Odd-Numbered Problems, and Looking Ahead.

Chapter 1:  Chemistry:  It’s All About “Stuff”

1.1    “Stuff” is Matter
1.2    Gas Behavior — An Introduction to the Behavior of Matter
1.3    Classifying Matter : Mixture or Pure Substance
1.4    Elements, Compounds, and the Periodic Table
1.5    How Matter Changes

Chapter 2:  Atoms, Radioactivity, and Ions
2.1    The Atom and Subatomic Particles
2.2    Atomic Number and Mass Number
2.3    Isotopes and Atomic Mass
2.4    Measuring Atoms: The Mole
2.5    Electron Arrangements
2.6    Radioactivity and Radioisotopes
2.7    Nuclear Equations and Radioactive Decay
2.8    Radiation Units and Half-Lives
2.9    Medical Applications for Radioisotopes

Chapter 3:  Compounds: Putting Particles Together
3.1    The Octet Rule
3.2    In Search of an Octet Part 1: Ion Formation
3.3    Ionic Compounds — Give and Take
3.4    In Search of an Octet Part 2: Covalent Bonding
3.5    Getting Covalent Compounds into Shape
3.6    Electronegativity and Molecular Polarity

Chapter 4:  Introduction to Organic Compounds
4.1    Alkanes — The Simplest Organic Compounds
4.2    Representing the Structures of Organic Compounds
4.3    Fatty Acids – Biological Hydrocarbons
4.4    Families of Organic Compounds — Functional Groups
4.5    Isomerism in Organic Compounds, Part 1
4.6    Isomerism in Organic Compounds, Part 2

Chapter 5:   Carbohydrates:  Life’s Sweet Molecules
5.1    Carbohydrates
5.2    Monosaccharide Structure
5.3    Oxidation and Reduction Reactions
5.4    Ring Formation — The Truth about Monosaccharide Structure
5.5    Disaccharides
5.6    Polysaccharides
5.7    Carbohydrates and Blood

Chapter 6: Intermolecular Forces: State Changes, Solubility, and Cell Membranes
6.1    Types of Intermolecular Forces
6.2    Intermolecular Forces and Solubility
6.3  Intermolecular Forces and Changes of State
6.4  Fats, Oils, and Margarine — Solid to Liquid and Back Again
6.5  Intermolecular Forces and the Cell Membrane

Chapter 7: Solution Chemistry:  How Sweet is Your Tea?
7.1    Solutions are Mixtures
7.2    Formation of Solutions
7.3    Chemical Equations for Solution Formation — Electrolytes
7.4    Concentration
7.5    Dilution
7.6    Osmosis and Diffusion
7.7    Transport Across Cell Membranes

Chapter 8:  Acids, Bases, and the Building Blocks of Life
8.1    Acids and Bases — Definitions
8.2    Strong Acids and Bases
8.3    Chemical Equilibrium
8.4    Weak Acids and Bases
8.5    pH and the pH scale
8.6    pKa 
8.7    Amino Acids:  Common Biological Weak Acids
8.8    Buffers:  An Important Property of Weak Acids and Bases
Chapter 9:  Proteins — Amides at Work
9.1 Amino Acids — A second look
9.2    Protein Formation
9.3    Protein Structure
9.4  Protein Denaturation
9.5  Sample Proteins  

Chapter 10:  Enzymes — Nature’s Chemists
10.1    Enzymes and Their Substrates
10.2    Enzyme Activity
10.3     Reaction Energetics and Thermodynamics
10.4      Reaction Energy Diagrams
10.5     Activation Energy (Ea)

Chapter 11:  Nucleic Acids — Big Molecules with a Big Role
11.1    Components of Nucleic Acids   
11.2    Nucleic Acid Formation
11.3      DNA
11.4      RNA and Protein Synthesis
11.5     Putting It Together:  The Genetic Code and Protein Synthesis
11.6     Genetic Mutations
11.7     Viruses
11.8    Recombinant DNA Technology

Chapter 12:  Food As Fuel — A Metabolic Overview
12.1  Overview of Metabolism
12.2  Metabolically Relevant Nucleotides
12.3  Digestion — From Fuel Molecules to Building Blocks
12.4  Glycolysis — From Building Blocks to Common Metabolites
12.5  The Citric Acid Cycle — Central Processing   
12.6  Electron Transport and Oxidative Phosphorylation
12.7  ATP Production
12.8  Other Fuel Choices