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PhysioEx(TM) 9.0: Laboratory Simulations in Physiology

By Peter Zao, Timothy N. Stabler, Lori A. Smith, Andrew Lokuta, Edwin Griff

Published by Pearson

Published Date: Sep 15, 2011


PhysioEx 9.0: Laboratory Simulations in Physiology is an easy-to-use laboratory simulation software and lab manual that consists of 12 exercises containing 66 physiology lab activities that can be used to supplement or substitute wet labs. PhysioEx allows you to repeat labs as often as you like, perform experiments without harming live animals, and conduct experiments that are difficult to perform in a wet lab environment because of time, cost, or safety concerns.


The PhysioEx 9.0 software features a brand new online format with step-by-step instructions and assessment so that everything you need to do and complete your lab is located in one convenient place. New Pre-lab and Post-lab Quizzes for each activity and Stop & Think and Predict Questions within the steps of each experiment help students make the connection between the activities and the physiological concepts they demonstrate. Your answers to all of these questions and the results from the experiments can be saved in a PDF Lab Report. The PhysioEx 9.0 CD-ROM comes packaged with every new copy of the PhysioEx 9.0 lab manual. Each new copy of the PhysioEx 9.0 lab manual also includes access to the online version of PhysioEx 9.0.


Note: For PhysioEx 9.0, there is one version only of PhysioEx. We have combined the previous A&P and Physiology versions of PhysioEx into one product.

Table of Contents

Exercise 1: Cell Transport Mechanisms and Permeability


Activity 1: Simulating Dialysis (Simple Diffusion)

Activity 2: Simulated Facilitated Diffusion

Activity 3: Simulating Osmotic Pressure

Activity 4: Simulating Filtration

Activity 5: Simulating Active Transport


Exercise 2: Skeletal Muscle Physiology


Activity 1: The Muscle Twitch and the Latent Period

Activity 2: The Effect of Stimulus Voltage on Skeletal Muscle Contraction

Activity 3: The Effect of Stimulus Frequency on Skeletal Muscle Contraction

Activity 4: Tetanus in Isolated Skeletal Muscle

Activity 5: Fatigue in Isolated Skeletal Muscle

Activity 6: The Skeletal Muscle Length-Tension Relationship

Activity 7: Isotonic Contractions and the Load-Velocity Relationship


Exercise 3: Neurophysiology of Nerve Impulses


Activity 1: The Resting Membrane Potential

Activity 2: Receptor Potential

Activity 3: The Action Potential: Threshold

Activity 4: The Action Potential: Importance of Voltage-Gated Na+ channels

Activity 5: The Action Potential: Measuring Its Absolute and Relative Refractory Periods

Activity 6: The Action Potential: Coding for Stimulus Intensity

Activity 7: The Action Potential: Conduction Velocity

Activity 8: Chemical Synaptic Transmission and Neurotransmitter Release

Activity 9: The Action Potential: Putting It All Together


Exercise 4: Endocrine System Physiology


Activity 1: Metabolism and Thyroid Hormone

Activity 2: Plasma Glucose, Insulin, and Diabetes Mellitus

Activity 3: Hormone Replacement Therapy

Activity 4: Measuring Cortisol and Adrenocorticotropic Hormone


Exercise 5: Cardiovascular Dynamics


Activity 1: Studying the Effect of Blood Vessel Radius on Blood Flow Rate

Activity 2: Studying the Effect of Blood Viscosity on Blood Flow Rate

Activity 3: Studying the Effect of Blood Vessel Length on Blood Flow Rate

Activity 4: Studying the Effect of Blood Pressure on Blood Flow Rate

Activity 5: Compensation: Studying the Effect of Blood Vessel Radius on Pump Activity

Activity 6: Studying the Effect of Stroke Volume on Pump Activity

Activity 7: Compensation in Pathological Cardiovascular Conditions


Exercise 6: Cardiovascular Physiology


Activity 1: Investigating the Refractory Period of Cardiac Muscle

Activity 2: Examining the Effect of Vagus Nerve Stimulation

Activity 3: Examining the Effect of Temperature on Heart Rate

Activity 4: Examining the Effects of Chemical Modifiers on Heart Rate

Activity 5: Examining the Effects of Various Ions on Heart Rate


Exercise 7: Respiratory System Mechanics


Activity 1: Measuring Respiratory Volumes and Calculating Capacities

Activity 2: Comparative Spirometry

Activity 3: Effect of Surfactant and Intrapleural Pressure on Respiration


Exercise 8: Chemical and Physical Processes of Digestion


Activity 1: Assessing Starch Digestion by Salivary Amylase

Activity 2: Exploring Amylase Substrate Specificity

Activity 3: Assessing Pepsin Digestion of Protein

Activity 4: Assessing Lipase Digestion of Fat


Exercise 9: Renal System Physiology


Activity 1: Renal System Physiology

Activity 2: The Effect of Pressure on Glomerular Filtration

Activity 3: Renal Response to Altered Blood Pressure

Activity 4: Solute Gradients and Their Impact on Urine Concentration

Activity 5: Reabsorption of Glucose via Carrier Proteins

Activity 6: The Effect of Hormones on Urine Formation


Exercise 10: Acid-Base Balance


Activity 1: Hyperventilation

Activity 2: Rebreathing

Activity 3: Renal Responses to Respiratory Acidosis and Respiratory Alkalosis

Activity 4: Respiratory Responses to Metabolic Acidosis and Metabolic Alkalosis


Exercise 11: Blood Analysis


Activity 1: Hematocrit Determination

Activity 2: Erythrocyte Sedimentation Rate

Activity 3: Hemoglobin Determination

Activity 4: Blood Typing

Activity 5: Blood Cholesterol


Exercise 12: Serological Testing


Activity 1: Using Direct Fluorescent Antibody Technique to Test for Chlamydia

Activity 2: Comparing Samples with Ouchterlony Double Diffusion

Activity 3: Indirect Enzyme-Linked Immunosorbent Assay (ELISA)

Activity 4: Western Blotting Technique